Brown Press release highlights Tapinos's new start up company for first in class therapeutics targeting cancer

“Through cutting-edge research, Nikos Tapinos, an associate professor of neurosurgery and neuroscience at Brown, is now advancing breakthroughs in RNA technology to take on hard-to-treat malignancies”

By unlocking an understanding of how to modify RNA molecules produced within a cancer cell, Tapinos developed a new RNA therapeutic discovery platform, named the Epi-CODE™ RNA Platform. Leveraging the knowledge of RNA modifications of cancer stem cells, he developed RNA therapeutics that can stop tumor growth and increase overall survival rates for hard-to-treat cancers, including glioblastoma, melanoma, colorectal, ovarian and non-small cell lung cancer. Findings from preclinical research show excellent efficacy in mouse models of cancer”

Tapinos co-founded Tinos Therapeutics, Inc. in March with pharmaceutical and biotech executive Wendy Perrow, who serves as CEO. The startup’s team is now focused on raising funding to further test the RNA platform’s efficacy through clinical trials and then ultimately FDA approval, which they hope to secure by 2025.”

Congratulations Ola! Ola Hassan, a PhD student at the Tapinos Lab has been selected as a young scholar to join the 4th WLF!

The World Laureates Association has distinguished Ola in a pool of highly accomplished candidates around the world. The selection has been made after a nomination done by the Pathobiology graduate program then by Brown University graduate school.

The forum’s vision is to support the young scientists worldwide by communicating with science masters (including Nobel Laureates) and fully demonstrate their academic achievements, talents and Innovative ideas . Read more here

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Congratulations to Blessing!

Congratulations to Blessing Akobundu, a talented 5th year PhD student at the Tapinos Lab. Blessing has been selected for a funded fellowship by Celdara Medical (with the support from NIH) to gain a real work experience in biotechnology.

https://celdaramedical.com/celdara-medical-names-entrepreneur-fellows/

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Congratulations! John Zepecki, a PhD student at the Tapinos Lab was awarded 2021 Frederic Poole Gorham Pre-doctoral Fellow!

John Zepecki has been selected as a 2021 Frederic Poole Gorham Pre-doctoral Fellow. This designation of a meritorious student is made by the Associate Dean for Graduate and Postdoctoral Studies in consultation with Graduate Program Directors, in memory of Professor Gorham. John is conducting his thesis work in the lab of Nikos Tapinos. Congratulations John!

Nikos Tapinos, MD, PhD Receives 2020-2021 Dean’s Award for Excellence in Graduate and/or Postdoctoral Teaching and Mentoring in Biological Sciences.

Nikos Tapinos, MD, PhD. was selected by the Brown BioMed Leadership team to receive the 2020-2021 Dean’s Award for Excellence in Graduate and/or Postdoctoral Teaching and Mentoring in Biological Sciences. This award recognizes a Brown faculty member (campus or hospital-based) in the Division of Biology and Medicine for outstanding teaching and mentoring of graduate students and postdoctoral scholars.

Link is here

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Providence Business News is reporting Dr Tapinos's accomplishments in cancer work!


“He (Dr Tapinos) is one of my finest colleagues – an outstanding researcher and a terrific mentor. I expect that soon he will cement his worldwide reputation as a creative leader in the fields of glial cell biology and neuro-oncology” Dr. Ziya L. Gokaslan, Lifespan’s neurosurgeon-in-chief and clinical director of the Norman Prince Neurosciences Institute comment on Dr Tapinos and who nominated Dr Tapinos for the honor

Read the article here!

Congratulations! Dr. Tapinos receives the 2020 Bruce Selya Research Excellence Award for his outstanding biomedical research!


”The nomination describes in detail how innovative work in Dr. Tapinos's laboratory has led to a broad array of advancements in the highly complex science of treating certain tumors. Intellectual property developed from his work includes drug delivery methods, techniques to lure migrating tumor cells towards targeted regions in the brain, development of novel antibodies for cancer therapy, development of RNA therapeutics against eRNA targets in glioblastoma and the identification of drugs now in preparation for human clinical trials.”

“Dr. Tapinos’s notable research grant awards include a current $4 million, four-year grant from the Alpert Foundation for which he is co-Primary Investigator, supporting, Investigation of the role of epigenetics in adult and pediatric malignant glioma.”

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